Become a research volunteer.

niCVRI runs an integrated clinical development platform — actively enrolling patients in trials that target every layer of cardiovascular disease, from genetics to imaging to inflammation. Patient participation makes every discovery possible.

How Patient Volunteers Help

Our investigator-led trials run in partnership with sponsors whose drugs and devices will reshape cardiac care nationwide. By enrolling, patients get early access to next-generation therapies — and contribute directly to the science that will help future patients.

  • Therapeutic areas include elevated lipoprotein(a), HFpEF with metabolic disease, vascular inflammation, ASCVD, calcific aortic valve stenosis, abdominal aortic aneurysm, and AI-detected coronary artery disease.
  • Trials run at sites in Beverly Hills and New York with multi-site recruitment underway at major academic centers.
  • Every participant is cared for by working clinician-scientists who run the trial and provide hands-on follow-up.
  • Participation is voluntary, reviewed by an Institutional Review Board, and protected by federal research-subject standards.

300+

Patient visits in 2025

Across active, recruiting, and long-term follow-up studies — covering the full spectrum of cardiovascular disease.

12

Active & pending trials

Each FDA-track therapy or AI tool whose effectiveness depends, in part, on niCVRI investigator data.

25+

Patients in long-term follow-up

Ongoing surveillance and care that continues well beyond trial completion.